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秦公煒博士論文著作列表

  1. Xie X, Hu H, Tong X, Li L, Liu X, Chen M, Yuan H, Xie X, Li Q, Zhang Y, Ouyang H, Wei M, Huang J, Liu P, Gan W, Liu Y, Xie A, Kuai X, Chirn GW, Zhou H, Zeng R, Hu R, Qin J, Meng FL, Wei W, Ji H, Gao D.，“The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168.” Nat Cell Biol. 2018 Mar;20(3):320-331
  2. Chen MW, Chen H, Wang MH, Shou T, Shi YF, Guo QS, Shang YH, Hu J, Liu C, Dai L, Zhang P, Chirn GW, Wang K, Yao M. “The landscape of kinase fusions in 445 Chinese NSCLC patients.” Ann Oncol. 2017 Oct;28 Suppl 7:vii16
  3. Ali SM, Yao M, Yao J, Wang J, Cheng Y, Schrock AB, Chirn GW, Chen H, Mu S, Gay L, Elvin JA, Suh J, Miller VA, Stephens PJ, Ross JS, Wang K.,"Comprehensive genomic profiling of different subtypes of nasopharyngeal carcinoma reveals similarities and differences to guide targeted therapy." Cancer. 2017 Sep 15;123(18):3628-3637.
  4. Toombs JA, Sytnikova YA, Chirn GW, Ang I, Lau NC, Blower MD., "Xenopus Piwi proteins interact with a broad proportion of the oocyte transcriptome." RNA. 2017 Apr;23(4):504-520.
  5. Chirn GW, Rahman R, Sytnikova YA, Matts JA, Zeng M, Gerlach D, Yu M, Berger B, Naramura M, Kile BT, Lau NC., "Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals." PLoS Genet. 2015 Nov 20;11(11)
  6. Rahman R, Chirn GW, Kanodia A, Sytnikova YA, Brembs B, Bergman CM, Lau NC., "Unique transposon landscapes are pervasive across Drosophila melanogaster genomes." Nucleic Acids Res. 2015 Dec 15;43(22):10655-72.
  7. Post C, Clark JP, Sytnikova YA, Chirn GW, Lau NC., "The capacity of target silencing by Drosophila PIWI and piRNAs." RNA. 2014 Dec;20(12):1977-86.
  8. Yang W, Wu JM, Bi AD, Ou-yang YC, Shen HH, Chirn GW, Zhou JH, Weiss E, Holman EP, Liao DJ, "Possible Formation of Mitochondrial-RNA Containing Chimeric or Trimeric RNA Implies a Post-Transcriptional and Post-Splicing Mechanism for RNA Fusion," PLoS One. 2013 Oct 24;8(10)
  9. Matts JA, Sytnikova Y, Chirn GW, Igloi GL, Lau NC, "Small RNA library construction from minute biological samples." Methods Mol Biol. 2014;1093:123-36.
  10. Pennington KL, Marr SK, Chirn GW, Marr MT 2nd., "Holo-TFIID controls the magnitude of a transcription burst and general fine-tuning of transcription," Proc Natl Acad Sci USA. 2013 May 7; 110(19): 7678-83
  11. Sims HI, Chirn GW, Marr MT 2nd., “Single nucleotide in the MTF-1 binding site can determine metal-specific transcription activation,” Proc Natl Acad Sci USA. 2012 Oct 9;109(41):16516-21.
  12. Hall S, Chirn GW, Lau N, Sengupta P, "RNAi pathways contribute to developmental history-dependent phenotypic divergence in C. elegans." RNA, 2013 Mar; 19(3): 306-19
  13. Ma Q, Chirn GW, Szustakowski JD, Bakhtiarova A, Kosinski PA, Kemp D, Nirmala N., “Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profiles.” BioData Min. 2008 Jul 17;1(1):4.
  14. Young DW, Bender A, Hoyt J, McWhinnie E, Chirn GW, Tao CY, Tallarico JA, Labow M, Jenkins JL, Mitchison TJ, Feng Y., Integrating high-content screening and ligand-target prediction to identify mechanism of action. Nat Chem Biol. 2008 Jan;4(1):59-68.
  15. Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research, Saxena R, Voight B, Lyssenko V, Burtt1 N, de Bakker P, Chen H, Roix J, Kathiresan S, Hirschhorn J, Daly M, Hughes T, Groop L, Altshuler D, Almgren P, Florez J, Meyer J, Ardlie K, Bostrom K, Isomaa B, Lettre G, Lindblad U, Lyon H, Melander O, Newton-Cheh C, Nilsson P, Orho-Melander M, Rastam R, Speliotes E, Taskinen M, Tuomi T, Guiducci C, Berglund A, Carlson J, Gianniny L, Hackett R, Hall L, Holmkvist J, Laurila E, Sjogren M, Sterner M, Surti A, Svensson M, Svensson M, Tewhey R, Blumenstiel B, Parkin M, DeFelice M, Barry R, Brodeur W, Camarata J, Chia N, Fava M, Gibbons J, Handsaker B, Healy C, Nguyen K, Gates C, Sougnez C, Gage D, Nizzari M, Gabriel S, Chirn GW, Ma Q, Parikh H, Richardson D, Ricke D, Purcell S, “Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.” Science. 2007 June 1; 316(5829):1331-6.
  16. Plikat U, Voshol H, Dangendorf Y, Wiedmann B, Devay P, Muller D, Wirth U, Szustakowski J, Chirn GW, Inverardi B, Puyang X, Brown K, Kamp H, Hoving S, Ruchti A, Brendlen N, Peterson R, Buco J, Oostrum J, Peitsch MC. “From proteomics to systems biology of bacterial pathogens: approaches, tools, and applications.” Proteomics. 2007 Mar;7(6):992-1003.
  17. Ma Q, Chirn GW, Cai R, Szustakowski JD, Nirmala NR. “Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural networks.” BMC Bioinformatics. 2005 Oct 3; 6:242.
  18. Daouti S, Latario B, Nagulapalli S, Buxton F, Uziel-Fusi S, Chirn GW, Bodian D, Song C, Labow M, Lotz M, Quintavalla J, Kumar C. “Development of comprehensive functional genomic screens to identify novel mediators of osteoarthritis.” Osteoarthritis Cartilage. 2005 Jun;13(6):508-18.
  19. Pain D, Chirn GW, Strassel C, Kemp DM, “Multiple retropseudogenes from pluripotent cell-specific gene expression indicates a potential signature for novel gene identification.” J Biol Chem. 2005 Feb 25;280(8):6265-8.
  20. Iourgenko V, Zhang W, Mickanin C, Daly I, Jiang C, Hexham JM, Orth AP, Miraglia L, Meltzer J, Garza D, Chirn GW, McWhinnie E, Cohen D, Skelton J, Terry R, Yu Y, Bodian D, Buxton FP, Zhu J, Song C, Labow MA, “Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.” Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12147-52.
  21. Chanda SK, White S, Orth AP, Reisdorph R, Miraglia L, Thomas RS, DeJesus P, Mason DE, Huang Q, Vega R, Yu DH, Nelson CG, Smith BM, Terry R, Linford AS, Yu Y, Chirn GW, Song C, Labow MA, Cohen D, King FJ, Peters EC, Schultz PG, Vogt PK, Hogenesch JB, Caldwell JS, “Genome-scale functional profiling of the mammalian AP-1 signaling pathway,” Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12153-8. Epub 2003 Sep 26.
  22. A.S. Robeva, Y. Yan-Neale, P. Burfeind, D.L. Bodian, G.-W. Chirn, F.Kolbinger, M. Labow and R.D.W. Vallon, “Rapid Expression Cloning of Receptors Using Epitope-Tagged Ligands and High-Speed Cell Sorting,” Cytometry 51A:59-67 (2003).
  23. J.T.L.Wang, T.G.Marr, S.Rozen, D.Shasha, B.A.Shapiro, G.-W.Chirn, Z.Wang and K.Zhang," Patern Discovery and Classification in Biosequences," in Pattern Discovery in Biomolecular Data, (eds. J.T.L.Wang, B.A.Shapiro and D.Shasha), Chapter 4, Oxford University Press.
  24. Craig C, Race E, Sheldon J, Whittaker L, Gilbert S, Moffatt A, Rose J, Dissanayeke S, Chirn GW, Duncan IB, Cammack N, "HIV protease genotype and viral sensitivity to HIV protease inhibitors following saquinavir therapy," AIDS, 1998 Sep 10;12(13):1611-1618
  25. Wang J, Marr T, Shasha D, Shapiro B, Chirn GW and Lee T, "Complementary Classification Approaches for Protein Sequences," Protein Engineering, vol.9, no.5, pp.381-386, 1996.
  26. Wang J, Zhang K, Chirn GW, "Algorithms for Approximate Graph Matching," Information Sciences, vol.82, pp.45-74, 1995. 、
  27. Wang J, Marr T, Shasha D, Shapiro B, Chirn GW, "Discovering Active Motifs in Sets of Related Protein Sequences and Using Them for Classification," Nucleic Acids Research, vol.22, no.14, pp.2769-2775, 1994. 、
  28. Wang J, Chirn GW, Marr T, Shapiro B, Shasha D, Zhang K, "Combinatorial Pattern Discovery for Scientific Data: Some Preliminary Results," Proceedings of the 1994 ACM SIGMOD International Conference on Management of Data, Minneapolis, Minnesota, pp.115-125, May 1994.、
  29. Wang J, Zhang K, Chirn GW, "The Approximate Graph Matching Problem," Proceedings of the 12th International Conference on Pattern Recognition, Jerusalem, Israel, Vol.2, pp.284-288, Oct. 1994.

 

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